Principles of gene manipulation and genomics /

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Autore principale: Primrose, S. B.
Altri autori: Twyman, Richard M.
Natura: Libro
Lingua:inglese
Pubblicazione: Malden, MA Oxford Blackwell Pub. 2006.
Edizione:7th ed.
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Accesso online:Table of contents
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Sommario:
  • Gene manipulation in the post-genomics era
  • Basic techniques
  • Cutting and joining DNA molecules
  • Basic biology of plasmid and phage vectors
  • Cosmids, phasmids, and other advanced vectors
  • Gene cloning strategies
  • Sequencing genes and short stretches of DNA
  • Changing genes : site-directed mutagenesis and protein engineering
  • Bioinformatics
  • Cloning in bacteria other than Escherichia coli
  • Cloning in Saccharomyces cerevisiaea and other fungi
  • Gene transfer to animal cells
  • Genetic manipulation of animals
  • Gene transfer to plants
  • Advanced transgenic technology
  • The organization and structure of genomes
  • Mapping and sequencing genomes
  • Comparative genomics
  • Large-scale mutagenesis and interference
  • Analysis of the transcriptome
  • Proteomics I : expression analysis and characterization of proteins
  • Proteomics II : analysis of protein structures
  • Proteomics III : protein interactions
  • Metabolomics and global biochemical networks
  • Applications of genomics : understanding the basis of polygenic disorders and identifying quantitative trait loci
  • Applications of recombinant DNA technology.