Chemistry and molecular aspects of drug design and action

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Other Authors: Rekka, E. A. (Editor), Kourounakis, P. N. (Editor)
Format: Book
Language:English
Published: Boca Raton CRC Press/Taylor & Francis 2008.
Subjects:
Pharmaceutical chemistry.
Drugs > Design.
Chemistry, Pharmaceutical.
Drug Design.
Pharmacologic Actions.
Online Access:Table of contents only
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Table of Contents:
  • Inflammatory mechanisms in Alzheimer's disease and other neurodegenerative disorders / Joseph Rogers ... [et al.]
  • Treatment development strategies for Alzheimer's disease / Ernst Wülfert
  • Lipoprotein-associated phospholipase A₂ as a new prognostic factor for coronary artery disease / Alexandros D. Tselepis
  • New molecular targets for the prevention and treatment of gastrointestinal ulcers and inflammation / Sandor Szabo ... [et al.]
  • Stress activates corticotropin releasing : factor signaling pathways : implication in functional bowel disorders / Yvette Taché
  • Design, synthesis, and pharmacological evaluation of high-affinity and selectivity sigma-1 and sigma-2 receptor ligands / Jacques H. Poupaert
  • Synthesis of biologically active taxoids / K.C. Nicolaou and R.K. Guy
  • From the molecular pharmacology to the medicinal chemistry of cannabinoids / Didier M. Lambert
  • An appraisal of fomocaines : current situation and outlook / Herbert Oelschläger and Andreas Seeling
  • Ligands for the GABA recognition site at the GABAA receptor : structure-activity studies / Bente Frølund ... [et al.]
  • Strategies for development of new lead structures for inhibition of acetylcholinesterase / Petra Kapkova ... [et al.]
  • Discovery of potent and selective inhibitors of human aldosterone synthase (CYP11B2) : a new target for the treatment of congestive heart failure and myocardial fibrosis--a review / R.W. Hartmann ... [et al.]
  • Thiocarboxanilides : a new class of nonnucleoside reverse transcriptase inhibitors (NNRTIs) with great potential for the treatment of human immunodeficiency virus type 1 (HIV-1) infections / E. De Clercq, A. Karlsson, and J. Balzarini
  • Histamine H₃-receptor agonists and antagonists : chemical, pharmacological, and clinical aspects / Holger Stark and Walter Schunack
  • Anti-inflammatory actions of flavonoids and structural requirements for new design / Theoharis C. Theoharides
  • Molecular mechanisms of H₂O₂-induced DNA damage : the action of desferrioxamine / M. Tenopoulou, P.-T Doulias, and D. Galaris
  • LNA (locked nucleic acid) and functionalized LNA : towards efficient gene targeting / Jesper Wengel
  • The effect of diet on drug metabolism / K.J. Netter
  • Cytochromes P450 in the metabolism and bioactivation of chemicals / Costas Ioannides
  • In vitro methods to measure drug metabolism and drug interactions in drug discovery and development / O. Pelkonen ... [et al.]
  • How to probe the sites of action of drug molecules / A. Makriyannis and F. Bitter
  • Physicochemical profiling in early drug discovery : new challenges at the age of high-throughput screen and combinatorial chemistry / Bernard Faller
  • Drug membrane interaction and its importance for drug efficacy / J.K. Seydel ... [et al.]
  • The fight against AIDS : new avenues for inhibiting reverse transcriptase (RT), and old target / Maurizio Botta ... [et al.].

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