Understanding mucosal responsiveness: lessons from enteric bacterial pathogens
Mucosal immune responses must discriminate between commensal flora within the lumen and potential pathogens. These responses are highly adapted to induce protection without excessive inflammation. The balances that regulate mucosal immune and inflammatory responses have to be understood if effective...
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| Formato: | Journal Article |
| Idioma: | inglês |
| Publicado em: |
2018
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| Acesso em linha: | https://demo7.dspace.org/handle/123456789/215 |
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| _version_ | 1860822454955409408 |
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| author | Simmons, Cameron |
| author_browse | Simmons, Cameron |
| author_facet | Simmons, Cameron |
| author_sort | Simmons, Cameron |
| collection | DSpace |
| description | Mucosal immune responses must discriminate between commensal flora within the lumen and potential pathogens. These responses are highly adapted to induce protection without excessive inflammation. The balances that regulate mucosal immune and inflammatory responses have to be understood if effective mucosal immunity is to be induced through local immunization. This review will summarize some of the lessons learnt from studies of antigens derived from enteric bacterial pathogens and discuss how the gastrointestinal epithelia can 'fight back' when it encounters pathogens. |
| format | Journal Article |
| id | oai:localhost:123456789-215 |
| institution | DSPACE.FCHPT |
| language | English |
| publishDate | 2018 |
| publishDateRange | 2018 |
| publishDateSort | 2018 |
| record_format | dspace |
| spelling | oai:localhost:123456789-2152021-04-07T16:30:08Z Understanding mucosal responsiveness: lessons from enteric bacterial pathogens Simmons, Cameron Mucosal immune responses must discriminate between commensal flora within the lumen and potential pathogens. These responses are highly adapted to induce protection without excessive inflammation. The balances that regulate mucosal immune and inflammatory responses have to be understood if effective mucosal immunity is to be induced through local immunization. This review will summarize some of the lessons learnt from studies of antigens derived from enteric bacterial pathogens and discuss how the gastrointestinal epithelia can 'fight back' when it encounters pathogens. 2018-09-14T11:15:08Z 2017-07-05T05:02:05Z 2018-09-14T11:15:08Z 2001-06-01 Journal Article https://demo7.dspace.org/handle/123456789/215 English |
| spellingShingle | Simmons, Cameron Understanding mucosal responsiveness: lessons from enteric bacterial pathogens |
| title | Understanding mucosal responsiveness: lessons from enteric bacterial pathogens |
| title_full | Understanding mucosal responsiveness: lessons from enteric bacterial pathogens |
| title_fullStr | Understanding mucosal responsiveness: lessons from enteric bacterial pathogens |
| title_full_unstemmed | Understanding mucosal responsiveness: lessons from enteric bacterial pathogens |
| title_short | Understanding mucosal responsiveness: lessons from enteric bacterial pathogens |
| title_sort | understanding mucosal responsiveness lessons from enteric bacterial pathogens |
| url | https://demo7.dspace.org/handle/123456789/215 |
| work_keys_str_mv | AT simmonscameron understandingmucosalresponsivenesslessonsfromentericbacterialpathogens |