Recent advances in dengue pathogenesis and clinical management
This review describes and commentates on recent advances in the understanding of dengue pathogenesis and immunity, plus clinical research on vaccines and therapeutics. We expand specifically on the role of the dermis in dengue virus infection, the contribution of cellular and humoral immune response...
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| Format: | Journal Article |
| Sprache: | Englisch |
| Veröffentlicht: |
2018
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| Online-Zugang: | https://demo7.dspace.org/handle/123456789/235 |
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| _version_ | 1860822454959603712 |
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| author | Simmons, Cameron |
| author_browse | Simmons, Cameron |
| author_facet | Simmons, Cameron |
| author_sort | Simmons, Cameron |
| collection | DSpace |
| description | This review describes and commentates on recent advances in the understanding of dengue pathogenesis and immunity, plus clinical research on vaccines and therapeutics. We expand specifically on the role of the dermis in dengue virus infection, the contribution of cellular and humoral immune responses to pathogenesis and immunity, NS1 and mechanisms of virus immune evasion. Additionally we review a series of therapeutic intervention trials for dengue, as well as recent clinical research aimed at improving clinical diagnosis, risk prediction and disease classification. |
| format | Journal Article |
| id | oai:localhost:123456789-235 |
| institution | DSPACE.FCHPT |
| language | English |
| publishDate | 2018 |
| publishDateRange | 2018 |
| publishDateSort | 2018 |
| record_format | dspace |
| spelling | oai:localhost:123456789-2352021-04-07T16:30:09Z Recent advances in dengue pathogenesis and clinical management Simmons, Cameron This review describes and commentates on recent advances in the understanding of dengue pathogenesis and immunity, plus clinical research on vaccines and therapeutics. We expand specifically on the role of the dermis in dengue virus infection, the contribution of cellular and humoral immune responses to pathogenesis and immunity, NS1 and mechanisms of virus immune evasion. Additionally we review a series of therapeutic intervention trials for dengue, as well as recent clinical research aimed at improving clinical diagnosis, risk prediction and disease classification. 2018-09-14T11:15:12Z 2017-05-24T05:12:48Z 2018-09-14T11:15:12Z 2015-09-03 2015-09-03 2015-09-03 2015-09-03 2015-09-03 2015-09-03 2015-09-03 2015-09-03 2015-09-03 2015-12-10 Journal Article https://demo7.dspace.org/handle/123456789/235 English |
| spellingShingle | Simmons, Cameron Recent advances in dengue pathogenesis and clinical management |
| title | Recent advances in dengue pathogenesis and clinical management |
| title_full | Recent advances in dengue pathogenesis and clinical management |
| title_fullStr | Recent advances in dengue pathogenesis and clinical management |
| title_full_unstemmed | Recent advances in dengue pathogenesis and clinical management |
| title_short | Recent advances in dengue pathogenesis and clinical management |
| title_sort | recent advances in dengue pathogenesis and clinical management |
| url | https://demo7.dspace.org/handle/123456789/235 |
| work_keys_str_mv | AT simmonscameron recentadvancesindenguepathogenesisandclinicalmanagement |