miR-17-92/p38α dysregulation enhances Wnt signal and selects Lgr6+ cancer stem cell like cells during human lung adenocarcinoma progression

Defining the molecular and cellular roots of lung cancer relapse after initial treatment remains an imperative to improve survival. Here we report that the lung stem cell marker Lgr6 becomes enriched in non-small cell lung cancer (NSCLC) cells during malignant progression. Lgr6+ NSCLC cells displaye...

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Autori principali: Guinot, Anna, Oeztuerk-Winder, Feride, Ventura, Juan-Jose
Lingua:inglese
Pubblicazione: American Association for Cancer Research 2019
Accesso online:https://demo7.dspace.org/handle/123456789/443
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Documenti analoghi: miR-17-92/p38α dysregulation enhances Wnt signal and selects Lgr6+ cancer stem cell like cells during human lung adenocarcinoma progression