Genetic evidence for a link between favorable adiposity and lower risk of type 2 diabetes, hypertension and heart disease.

Recent genetic studies have identified some alleles associated with higher BMI but lower risk of type 2 diabetes, hypertension and heart disease. These "favorable adiposity" alleles are collectively associated with lower insulin levels and higher subcutaneous-to-visceral adipose tissue ratio and may...

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Main Authors: Yaghootkar, Hanieh, Lotta, Luca, Tyrrell, Jessica, Smit, Roelof AJ, Jones, Sam E, Donnelly, Louise, Beaumont, Robin, Campbell, Archie, Tuke, Marcus A, Hayward, Caroline, Ruth, Katherine S, Padmanabhan, Sandosh, Jukema, J Wouter, Palmer, Colin C, Hattersley, Andrew, Freathy, Rachel M, Langenberg, Claudia, Wareham, Nicholas, Wood, Andrew R, Murray, Anna, Weedon, Michael N, Sattar, Naveed, Pearson, Ewan, Scott, Robert, Frayling, Timothy M
Other Authors: Biology
Language:English
Published: American Diabetes Association 2019
Online Access:https://demo7.dspace.org/handle/123456789/457
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